Saving Lives
with Science
FAME
Functional Architecture of Mammals in their Environment
RESEARCH
Our research is driven by a deep commitment to improving human health and wellbeing by addressing some of today’s most pressing global challenges. We explore the complex interplay between the environment and human physiology, with a focus on environmental health, climate change, and occupational exposure to extreme conditions.
Our team investigates how heat, cold, altitude, and other environmental stressors impact the human body—particularly in the context of thermal strain, heat stress, and overall physical performance. We also conduct in-depth research on the biology of adipose tissue, uncovering its critical role in energy regulation, thermoregulation, and metabolic health.
From laboratory experiments to field studies, our multidisciplinary approach bridges basic science and real-world applications. Whether it’s protecting outdoor workers from extreme heat or understanding how climate change affects human physiology, our research aims to generate knowledge that transforms lives and informs effective solutions.
Vision and History
People’s lives are dependent on the environment not only for good health, but also for education, housing, economic opportunity, and social connection. How can we and future generations sustainably thrive in the midst of a profoundly changing environment?
At FAME lab, we imagine a world where the vast majority of people understand how the environment impacts their lives and plan their activities in harmonious accordance with the long-term well-being of humanity. Our goal is to get closer to that, to stand as a beacon that points towards that, and to offer the tools we can and inspire others to help us build tools to get to that world. We strive to help society understand and adapt to the impacts of environmental factors. Understanding and addressing the drivers of poor οutcomes in health, productivity, and performance will, undoubtedly, accelerate improvements in quality of life for all people – sustainably and justly.
FAME lab was founded in 2008 to study the Functional Architecture of Mammals in their Environment. We have participated in >20 large-scale projects funded by the EU and other international organizations (>19M euro funding in the last decade), we have published >200 papers in scientific journals, and we have presented our work in >300 international conferences.
FAME Lab supports these and other types of stakeholders:
Research Organizations
High-quality research and publications.
Global network of partners.
Policy makers
Contribution to legislation.
Policy-relevant science.
Industrial actors
Product conceptualization, development & verification.
Patent applications.
Civil Society Organizations
Societal impact assessment.
Community-driven actions.
Open-innovatioon.
Educational Organizations
Implementation of courses for people of all ages.
Sports teams
Supporting athletes & teams.
Expeditions in extreme environments.
Our Impact in Numbers
We envision a world where people understand how the environment affects their lives and shape their goals and activities with the long-term well-being of humanity in mind.
Our work has been cited
times in peer-reviewed journal articles.
We have published
scientific papers.
We have coordinated or participated in
internationally funded research projects.
We have authored
reports in collaboration with international organizations.
Read our
Publications
Bovine Colostrum Supplementation Improves Bone Metabolism in an Osteoporosis-Induced Animal Model
Kydonaki EK, Freitas L, Fonseca BM, Reguengo H, Raposo Simón C, Bastos AR, Fernandes EM, Canadas RF, Oliveira JM, Correlo VM, Reis RL, Vliora M,
Natural Histogel-Based Bio-Scaffolds for Sustaining Angiogenesis in Beige Adipose Tissue
Di Somma M, Schaafsma W, Grillo E, Vliora M, Dakou E, Corsini M, Ravelli C, Ronca R, Sakellariou P, Vanparijs J, Castro B, Mitola S.
Role of VEGFs in metabolic disorders
di Somma M, Vliora M, Grillo E, Castro B, Dakou E, Schaafsma W, Vanparijs J, Corsini M, Ravelli C, Sakellariou E, Mitola S. Role of
Adipose Tissue Metabolism in Response to Food Intake
Carrillo, A. E., & Vliora, M. (2023). Adipose Tissue Metabolism in Response to Food Intake. Nutrients, 15(22), 4811. https://doi.org/10.3390/nu15224811 The quality and quantity of the food we
An Exploratory Investigation of Heart Rate Variability in Response to Exercise Training and Detraining in Young and Middle-Aged Men
Carrillo, A.E.; Dinas, P.C.; Gkiata, P.; Ferri, A.R.; Kenny, G.P.; Koutedakis, Y.; Jamurtas, A.Z.; Metsios, G.S.; Flouris, A.D. An Exploratory Investigation of Heart Rate Variability
Brief extreme passive heat exposure leads to elevated biomarkers of systemic inflammation and acute kidney injury in older vs young adults
Vliora M, McCormick JJ, King KE, Gkiata P, Kaltsatou A, Flouris AD, Kenny GP. Brief extreme passive heat exposure leads to elevated biomarkers of systemic
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