POSITIVe – FA1403 (Interindividual variation in response to consumption of plant food bioactives and determinants involved) was a recently started network approved and funded by the COST organization in the field of Food & Agriculture. It involved a total of 27 countries that devoted their work and cooperation to further understand the factors associated with human variability and its effects on the responsiveness to the intake of plant food bioactive compounds. The action was  chaired by Dr. Christine Morand (INRA, France) and co-chaired by Dr Francisco Tomas-Barberan (CEBAS-CSIC, Spain) who led the network with the cooperation and help of a Management Committee (MC) and a Steering Committee (SC) formed by members of the Action. FAME Lab was a participator in this action, which ran from 11/12/2014 to 10/12/2018.