02 Apr Acute effects of second-hand smoke on complete blood count
Dinas PC, Metsios GS, Jamurtas AZ, Tzatzarakis MN, Wallace Hayes A, Koutedakis Y, Tsatsakis AM, Flouris AD. Acute effects of second-hand smoke on complete blood count. Int J Environ Health Res. 2014;24(1):56-62. doi: 10.1080/09603123.2013.782603. Epub 2013 Apr 2. PMID: 23544435.
We assessed the acute effects of a 1-h exposure to second-hand smoke (SHS) on complete blood count (CBC) markers in a controlled simulated bar/restaurant environment. Nineteen adult never-smokers completed a 1-h .exposure to SHS at bar/restaurant levels, and a 1-h exposure to normal room air. Blood samples were collected at the baseline at 30 min during each exposure, and at 0, 0.5, 1, 2, 3, and 4 h after each exposure.
The values of white blood cells (WBC) at 1 h (p = 0.010), 3 h (p = 0.040), and 4 h (p = 0.008) following SHS were significantly increased compared with the baseline values. Also, there was a positive association between the WBC and cotinine levels (r = 0.28, p = 0.007). A 1-h exposure to SHS at bar/restaurant levels significantly increased the WBC for at least 4 h following the exposure time. This effect of SHS on WBC has dose-response characteristics and should be considered to prescribing CBC.
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