Exercise heat stress in patients with and without type 2 diabetes

FAME Lab - Exercise Heat Stress in Patients With and Without Type 2 DiabetesNotley SR, Poirier MP, Sigal RJ, D’Souza A, Flouris AD, Fujii N, Kenny GP. Exercise Heat Stress in Patients With and Without Type 2 Diabetes. JAMA. 2019 Oct 8;322(14):1409-1411. doi: 10.1001/jama.2019.10943. PMID: 31593261; PMCID: PMC6784783.


Performing exercise in the heat can increase the risk of health complications, especially among middle-aged and older adults who have impaired whole-body heat loss (WBHL) relative to young adults.1 That risk may be higher among patients with type 2 diabetes due to abnormalities in cutaneous vasodilation and sweating, which facilitate WBHL.2 However, repeated brief exercise for 7 days or more during heat exposure (heat acclimation) may mitigate this risk by enhancing WBHL.3 We therefore assessed whether type 2 diabetes impairs heat loss in physically active middle-aged and older adults during exercise heat stress and whether heat acclimation could offset any impairment.

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